Postdoctoral Positions
WEI XU LAB: posted Feb 2025
Postdoctoral position in Cancer Biology with the Department of Oncology at UW-Madison
Job summary: An immediate opening is available for a postdoctoral fellow to study transcriptional regulation and epigenetic mechanisms in breast cancer and Wilms tumor. Our lab has published significant findings in these areas (Wang L., Cancer Cell, 2014; Shishkova E, Nature Comm., 2017; Liu F. NCB, 2017; Liu F., EMBO J, 2021; Chan N. T., Nucleic Acids Res, 2022; Chan N. T., Science Advances, 2022; Ma G., Cell Reports Medicine, 2024). The research will focus on: utilizing genomic approaches (ChIP-Seq and scRNA-Seq) and proteomic methods, dissecting epigenetic mechanisms using cell-based and animal models, and career development including grant writing and skills essential for independence.
Required Qualifications
- Recent Ph.D. in molecular biology, cancer biology, or related field
- At least one first-author publication in major biology journals
- Strong background in molecular biology techniques
Preferred Skills
- Experience with standard molecular assays, cell culture, biochemistry, and flow cytometry
- Knowledge of computational genomic tools
- Expertise in transcription, signaling, or cancer epigenetics
- Experience with tumor organoid models and breast cancer rodent models (desirable but not required)
How to apply:
Please submit the following materials to wxu@oncology.wisc.edu:
- Cover letter
- Resume/CV
- Contact information for three referees
- Reprints of first-author publications
VALENTINA LO SARDO LAB: posted Oct 10, 2024
Postdoctoral fellow position in Stem Cell-based functional genomics
Job summary: A Postdoctoral fellow position is available in the laboratory of “Stem cell-based functional genomics of cardiovascular disease” directed by Dr. Valentina Lo Sardo. The lab is located in the Wisconsin Institute for Medical Research, Department of Cell and Regenerative Biology, at the School of Medicine and Public Health, University of Wisconsin-Madison. The lab has multiple NIH-funded projects focused on dissecting how genomic diversity across diverse human genetic ancestries affects cellular phenotypes in health and disease. We employ multidisciplinary approaches, including human induced pluripotent stem cells (iPSCs) derivation, iPSC differentiation in multiple cell types, CRISPR gene editing, bulk and single-cell RNA sequencing, ATAC sequencing, and computational biology. Our laboratory is affiliated with multiple centers at UW Madison, including the Stem Cell and Regenerative Medicine Center, the Cardiovascular Research Center, the Center for Genomic Science Innovation, the Human Genomics and Precision Medicine, the Carbone Cancer center. The trainee will receive multidisciplinary training in a highly collaborative and productive academic environment. Our lab promotes an inclusive and nurturing learning environment. The School of Medicine and Public Health has a deep and profound commitment to diversity, both as an end in itself and as a valuable means for eliminating health disparities.
As such, we strongly encourage applications from candidates who foster and promote the values of diversity and inclusion.
A successful candidate is expected to be a highly self-motivated, Ph.D. graduate with strong background in developmental biology, genetics, genomics, stem cell biology, or molecular biology. Strong publication record in related fields is required. Research experience in the stem cells field or experience with transcriptomic and epigenomic dataset analysis and interpretation is needed. The candidate should be capable of working both independently and collaboratively, under the supervision of the Principal Investigator, on one or two research projects.
To apply for this position, please send your CV, contact information of three referees, and a statement of research interest to Dr. Valentina Lo Sardo.
Salary is commensurate with experience and follows NIH guidelines.
About UW-Madison https://www.wisc.edu/about/
About the School of Medicine and Public Health https://www.med.wisc.edu/about-us/
Visit www.losardolab.com
check our publications on https://pubmed.ncbi.nlm.nih.gov/?term=lo+sardo+v&sort=date
JASON PETERS LAB: posted on October 10, 2024
Job Title: Research Associate (Postdoc) in Bacterial Genetics, Systems Biology, Synthetic Biology
Job Description: We seek a motivated candidate to work with us on our newly funded ARPA-H collaborative grant to combat antibiotic resistance (https://arpa-h.gov/news/darts/). We seek to identify gene/pathways involved in antibiotic resistance as well as novel physiological weaknesses that can be exploited in future therapies. The candidate will be responsible for constructing and phenotyping genome-scale CRISPRi libraries in Gram-negative pathogens—including clinical isolates, quantifying CRISPR screen results using Next Generation Sequencing (e.g., Illumina sequencing), bioinformatic analysis to identify and characterize screen hits, and follow up experiments to validate hit genes in terms of their contributions to viability/antibiotic resistance.
Requirements:
Ph.D. in Microbiology, Genetics, Molecular Biology, Systems Biology, Synthetic Biology, Biological/Biomolecular/Biomedical Engineering, or related fields.
Candidates must be within 1 year of Ph.D. graduation and Ph.D. must be granted by the start date.
Minimum Requirements:
- Strong written and oral communication skills to collaborate and communicate effectively with a team of researchers from diverse scientific backgrounds.
- Meticulous record keeping and ability to respond quickly to written requests for research progress.
Desired Qualifications:
- Strong candidates will have knowledge of and skills in microbiology, genetics, and molecular biology.
- Experience in the genetic manipulation of model and non-model microbes and/or synthetic biology, systems biology, and bioinformatics are highly desirable.
Required Application Materials:
Send a cover letter (up to 2 pages) describing your interest(s) in this position and relevant skills, a CV, and the name and contact information of three professional references. To apply – Please direct completed applications to Jason Peters (jason.peters@wisc.edu).