Staff Positions
DONNA WERLING Lab: posted May 9, 2024
Job Summary: The Data Scientist will perform data processing and statistical analyses on genomic data sets for research projects in the Werling Lab in the Department of Genetics. The goal of the Werling Lab is to understand the roles of genetic variation and sex differences in brain development and the biological mechanisms that influence risk for neurodevelopmental and psychiatric disorders. The Werling Lab utilizes genetics and functional genomics data to discover the molecular and cellular impacts of genetic variation and sex-differential biology, both from humans and from mouse models. For this position, the Werling lab is seeking an independent worker with excellent analytical, organizational, and collaborative skills to be involved in routine data analyses and the development and implementation of genomics data processing and analysis workflows for various data modalities generated from human and mouse bulk tissue and single nuclei.
The College of Agricultural and Life Sciences (CALS) and the Werling lab are committed to maintaining and growing a culture that embraces diversity, inclusion, and equity, believing that these values are foundational elements of our excellence and fundamental components of a positive and enriching learning and working environment for all students, faculty, and staff. At CALS, we acknowledge that bias, prejudice, racism, and hate have historically occurred in many forms that cause significant and lasting harm to members of our community. We commit to taking actions each day toward a college that is inclusive and welcoming to all.
Qualifications:
Required:
-Proficiency with Linux and a programming or statistical language such as R and/or Python
-Prior experience with statistics, bioinformatics, or computer science in a professional and/or student staff role (=1 year experience preferred)
-Ability to work independently and collaboratively on team-based projects within the lab and with collaborators
-Effective and flexible communication skills
Well-qualified applicants will also have the following preferred experience:
-Prior experience with processing high-throughput DNA or RNA sequencing data, including one or more of the following: quality assessment, read alignment to references, quantification, variant-calling
-Prior experience with analysis of sequencing data, such as differential expression of RNA-seq data and/or analysis of single-cell data
-Experience with analytical pipeline development, e.g. NextFlow, appreciated but not required.
More information and application: https://jobs.wisc.edu/jobs/data-scientist-madison-wisconsin-united-states-3f694e6f-4191-4fde-ba2d-144efad6486e
Postdoctoral Positions
VALENTINA LO SARDO LAB: posted Oct 10, 2024
Postdoctoral fellow position in Stem Cell-based functional genomics
Job summary: A Postdoctoral fellow position is available in the laboratory of “Stem cell-based functional genomics of cardiovascular disease” directed by Dr. Valentina Lo Sardo. The lab is located in the Wisconsin Institute for Medical Research, Department of Cell and Regenerative Biology, at the School of Medicine and Public Health, University of Wisconsin-Madison. The lab has multiple NIH-funded projects focused on dissecting how genomic diversity across diverse human genetic ancestries affects cellular phenotypes in health and disease. We employ multidisciplinary approaches, including human induced pluripotent stem cells (iPSCs) derivation, iPSC differentiation in multiple cell types, CRISPR gene editing, bulk and single-cell RNA sequencing, ATAC sequencing, and computational biology. Our laboratory is affiliated with multiple centers at UW Madison, including the Stem Cell and Regenerative Medicine Center, the Cardiovascular Research Center, the Center for Genomic Science Innovation, the Human Genomics and Precision Medicine, the Carbone Cancer center. The trainee will receive multidisciplinary training in a highly collaborative and productive academic environment. Our lab promotes an inclusive and nurturing learning environment. The School of Medicine and Public Health has a deep and profound commitment to diversity, both as an end in itself and as a valuable means for eliminating health disparities.
As such, we strongly encourage applications from candidates who foster and promote the values of diversity and inclusion.
A successful candidate is expected to be a highly self-motivated, Ph.D. graduate with strong background in developmental biology, genetics, genomics, stem cell biology, or molecular biology. Strong publication record in related fields is required. Research experience in the stem cells field or experience with transcriptomic and epigenomic dataset analysis and interpretation is needed. The candidate should be capable of working both independently and collaboratively, under the supervision of the Principal Investigator, on one or two research projects.
To apply for this position, please send your CV, contact information of three referees, and a statement of research interest to Dr. Valentina Lo Sardo.
Salary is commensurate with experience and follows NIH guidelines.
About UW-Madison https://www.wisc.edu/about/
About the School of Medicine and Public Health https://www.med.wisc.edu/about-us/
Visit www.losardolab.com
check our publications on https://pubmed.ncbi.nlm.nih.gov/?term=lo+sardo+v&sort=date
MATT ANDERSON LAB: posted on November 1, 2023
The lab is broadly interested in understanding how diversity in individual genomes and among microbes in communities contributes to adaptation. They are seeking one postdoctoral researcher to investigate the genetic determinants that distinguish commensal and virulence traits among strains of Candida albicans. They are also seeking another postdoctoral researcher to explore the eukaryotic constituents of the human microbiome using newly developed metagenomic techniques. More information is available here.
JASON PETERS LAB: posted on October 10, 2024
Job Title: Research Associate (Postdoc) in Bacterial Genetics, Systems Biology, Synthetic Biology
Job Description: We seek a motivated candidate to work with us on our newly funded ARPA-H collaborative grant to combat antibiotic resistance (https://arpa-h.gov/news/darts/). We seek to identify gene/pathways involved in antibiotic resistance as well as novel physiological weaknesses that can be exploited in future therapies. The candidate will be responsible for constructing and phenotyping genome-scale CRISPRi libraries in Gram-negative pathogens—including clinical isolates, quantifying CRISPR screen results using Next Generation Sequencing (e.g., Illumina sequencing), bioinformatic analysis to identify and characterize screen hits, and follow up experiments to validate hit genes in terms of their contributions to viability/antibiotic resistance.
Requirements:
Ph.D. in Microbiology, Genetics, Molecular Biology, Systems Biology, Synthetic Biology, Biological/Biomolecular/Biomedical Engineering, or related fields.
Candidates must be within 1 year of Ph.D. graduation and Ph.D. must be granted by the start date.
Minimum Requirements:
- Strong written and oral communication skills to collaborate and communicate effectively with a team of researchers from diverse scientific backgrounds.
- Meticulous record keeping and ability to respond quickly to written requests for research progress.
Desired Qualifications:
- Strong candidates will have knowledge of and skills in microbiology, genetics, and molecular biology.
- Experience in the genetic manipulation of model and non-model microbes and/or synthetic biology, systems biology, and bioinformatics are highly desirable.
Required Application Materials:
Send a cover letter (up to 2 pages) describing your interest(s) in this position and relevant skills, a CV, and the name and contact information of three professional references. To apply – Please direct completed applications to Jason Peters (jason.peters@wisc.edu).