A complete understanding of living creatures and their behaviors cannot come from studying only one aspect of physiology. Rather, it emerges from integrating knowledge across scales, domains, and dimensions to understand the network of cellular interactions underlying biological systems. While new methods of measuring physiology emerge at a rapid pace, how to understand that information in the context of living cells remains a major challenge. Researchers in the CGSI work collaboratively to understand cellular systems.
Credentials: CGSI Director, Genetics
Elucidating systems-level relationships between genotype-phenotype-environment in eukaryotic stress responses
The Hittinger Lab uses yeast carbon metabolism as a model for basic bioenergy, biomedical, and evolutionary research
Credentials: Biomedical Engineering
A bioengineering approach to understanding fundamental biological and medical questions in microbes, specifically model and pathogenic yeasts.
Elucidating bacterial genome evolution among plant and animal pathogens
Developing and applying genomic analysis methods to investigate the genetic complexity of adaptive trait evolution and reproductive isolation
Systems and synthetic biology approach to understanding and designing biology
Innovating massively parallel genomic technologies and applying to understand how the plasma membrane functions in all cells
Characterizing sex-differential risk mechanisms in autism and other neuropsychiatric disorders using functional genomics, human genetics and bioinformatics approaches