Research

Research in CGSI focuses on developing novel approaches and applications in the field of genomic science.  While many faculty span multiple areas, research falls into three themes:

Innovations in ‘Omic Technologies

Addressing new questions in biology requires the invention of new ways to interrogate biological systems.  Research in the CGSI is innovating through invention and application, with a focus on single-molecule DNA applications and mass spectrometry-based methods to interrogate molecules including proteins, RNAs, lipids, and metabolites. Find out more about CGSI faculty with a primary focus in this area here.

Innovations in Computational Approaches

Concurrent with technological advances, the CGSI faculty develop new computational and statistical approaches to handle new data types, integrate with existing knowledge, and answer new questions in biology. Close collaboration among researchers spanning research focal areas is accelerating the pace of invention and discovery, including co-development of computational methods to partner with novel genomic techniques. Find out more about CGSI faculty with a primary focus in this area here.

Integrative Genomics to Understand Complex Biological Systems

A complete understanding of living creatures and their behaviors cannot come from studying only one aspect of physiology.  Rather, it emerges from integrating knowledge across scales, domains, and dimensions to understand the network of cellular interactions underlying biological systems.  While new methods of measuring physiology emerge at a rapid pace, how to understand that information in the context of living cells remains a major challenge. Find out more about CGSI faculty with a primary focus in this area here.