Karl Broman

Professor of Biostatistics & Medical Informatics

2126 Genetics-Biotechnology Center, broman@wisc.edu,  608.262.4633

Departments

Biostatistics & Medical Informatics

Education

PhD (1997) Statistics, University of California, Berkeley
Postdoctoral fellowship (1997-1999) Marshfield Medical Research Foundation

Research Interests

Developing statistical methods for analysis of complex traits

Lab Website

https://kbroman.org

Representative Awards

  • 2016 Elected fellow of the American Statistical Association

Research

Karl is an applied statistician focusing on problems in genetics and genomics, particularly the analysis of meiotic recombination and the genetic dissection of complex traits in experimental organisms.  He is the chief developer of R/qtl, an R package for mapping quantitative trait loci (QTL) in experimental crosses, and is an enthusiastic developer of interactive data visualization tools for high-dimensional genetic data.

Representative Publications  (Google Scholar | PUBMED)

  • Broman, K. W., Gatti, D. M., Svenson, K. L., Sen, S. & Churchill, G. A. Cleaning Genotype Data from Diversity Outbred Mice. G3 (Bethesda) 9, 1571-1579, doi:10.1534/g3.119.400165 (2019).
  • Broman, K. W. et al. R/qtl2: Software for Mapping Quantitative Trait Loci with High-Dimensional Data and Multiparent Populations. Genetics 211, 495-502, doi:10.1534/genetics.118.301595 (2019).
  • Broman, K. W. et al. Identification and Correction of Sample Mix-Ups in Expression Genetic Data: A Case Study. G3 (Bethesda) 5, 2177-2186, doi:10.1534/g3.115.019778 (2015).
  • Broman, K. W. R/qtlcharts: interactive graphics for quantitative trait locus mapping. Genetics 199, 359-361, doi:10.1534/genetics.114.172742 (2015).